Front Side Bus Speed
Complex subject, but this has to do with being able to use different speed processors in the same motherboard. The FSB speed and a CPU multiplier are usually what you adjust to accomplish this, except more recent MB designs lock the multiplier and others don't let you change either setting. The settings still exist whether or not you have access to them, and may adjust themselves automatically for the CPU in use - which is definitely NOT meant to imply that any old cpu that fits in the slot will work.
For some systems, the FSB is related to the PCI bus speed, so changing it can adversely affect PCI cards.
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